Publikationen

 Paulista Markus MR ,Ittermann T , Mariño Coronado J,  Sabine Schipf S,  Bahls M, Könemann S, Chamling B, Völzke H, Teixeira Damasceno NR, Dias Santos R, Felix SB, Templin C, Steinhagen-Thiessen E, Dörr M; LDL-cholesterol, lipoprotein(a) and high-sensitivity low-density lipoprotein cholesterol, lipoprotein(a) and high-sensitivity C-reactive protein are independent predictors of cardiovascular eventsEur Heart J 2025 May 5:ehaf281. doi: 10.1093/eurheartj/ehaf281.


Meiners F, Kreikemeyer B, Newels P, Zude I, Walter MHartmann A, Palmer D, Fuellen G, Barrantes I; Strawberry dietary intervention influences diversity and increases abundances of SCFA-producing bacteria in healthy elderly people. Microbiol Spectr. 2025 Feb 4;13(2):e0191324. doi: 10.1128/spectrum.01913-24. Epub 2025 Jan 8


Luyken AK, Lappe C, Viard R,  Löhle M, Kleinlein HB, Kuchcinski G, Langner S, Wenzel A-M,  Walter M, Weber M-A, Storch A, Devos D, Walter U; High correlation of quantitative susceptibility mapping and echo intensity measurements of nigral iron overload in Parkinson's disease J Neural Transm (Vienna). 2025 Mar;132(3):407-417. doi: 10.1007/s00702-024-02856-1. Epub 2024 Nov 1

Spira D, Herbst S, Schwartzmann S, Dutrannoy V, Steinhagen-Thiessen E, Demuth I, Maurer L, Mai K, Spranger J, Mundlos S, Bobbert T.; A Novel Variant in the WRN Gene Detected in a Case of Early-Onset Severe Insulin Resistance Displaying Some but Not All Hallmarks of Progeroid Werner Syndrome. Diabetes Care 2024 May 1;47(5):798-802. doi: 10.2337/dc231479 


Knüppel F, Malchow S, Sun A, Hussong J, Hartmann A, Wurm FH, Torner B.; Viscosity Modeling for Blood and Blood Analog Fluids in Narrow Gap and High Reynolds NumbersFlows. Micromachines (Basel) 2024 Jun 16;15(6):793. doi: 10.3390/mi15060793


Projahn EF, Fuellen G, Walter M, Möller S.; Proposing candidate genes under telomeric control based on cross-species position dataNAR Genomics and Bioinformatics 2024 Apr 25;6(2):lqae037. doi: 10.1093/nargab/lqae037


Hahn O, Peters K, Hartmann A, Dannenberger D, Kalbe C.; Potential of animal-welfare compliant and sustainably sourced serum from pig slaughter blood. Cell Tissue Res. 2024 Sep; 397(3):205-214. doi: 10.1007/s00441-024-03904-8. Epub 2024 Jul 11


Luyken AK, Lappe C, Viard R, Löhle M, Kleinlein HR, Kuchcinski G, Langner S, Wenzel AM, Walter M, Weber MA, Storch A, Devos D, Walter U.; High correlation of quantitative susceptibility mapping and echo intensity measurements of nigral iron overload in Parkinson's diseaseJ Neural Transm (Vienna). 2025 Mar;132(3):407-417.  doi: 10.1007/s00702-024-02856-1. Epub 2024 Nov 1

Hartmann A, Secci R, Mensch J, Jäger KSteinhagen-Thiessen E, Barrantes I, Palmer D, Kowald A, Schwarz R, Hinz B, Weber D, Grune T, Hübbe P, Rimbach G, Rudolf H, Walter M, Fuellen G. 2023. High-dose polyphenol-rich nutrition improves lipid and inflammation profiles and triggers apoptotic signaling in healthy elderly people (the ErdBEHR Study). medRxiv; doi:10.59368/agingbio.20240020


Witkowski M, Nemet I, Alamri H, Wilcox J, Gupta N, Nimer N, Haghikia A, Li XS, Wu Y, Saha PP, Demuth I, König M, Steinhagen-Thiessen E, Cajka T, Fiehn O, Landmesser U, Wilson Tang WH, Hazen SL. The artificial sweetener erythritol and cardiovascular event risk. Nat Med 2023;29:710-718; DOI: 10.1038/s41591-023-02223 9   


Hartmann C, Herling L, HartmannA, Köckritz V, Fuellen G, Walter M, Hermann A. Systematic estimation of biological age of in vitro cell culture systems by an age-associated marker panel. Frontiers in Aging 2023;15:4:1129107; DOI: 10.3389/fragi.2023.1129107 


Secci R, Hartmann A, Walter M, Grab HJ, van der Auwera-Palitschka S, Kowald A, Palmer D, Rimbach G, Fuellen G, Barrantes I. Biomarkers of geroprotection and cardiovascular health: An overview of omics studies and established clinical biomarkers in the context of diet. Crit Rev Food Sci Nutr 2023;63:2426-2446; DOI: 10.1080/10408398.2021.1975638 


Ali JH, Abdeen Z, Azmi K, Berman T, Jager K, Barnett-Itzhaki Z, Walter M. Influence of exposure to pesticides on telomere length and pregnancy outcome: diethylphosphates but not Dimethylphosphates are associated with accelerated telomere attrition in a Palestinian cohort. Ecotoxicol Environ Saf 2023;256:114801. doi: 10.1016/j.ecoenv.2023.114801


Makhmudova U, Schatz U, Perakakis N, Kassner U, Schumann F, Axthelm C, Stürzebecher P, Sinning DL, Doevelaar A, Rohn B; Westhoff T, Vogt A, Scholl M, Kästner U, Geiling JA, Stach K, Mensch J, Lorenz E, Paitazoglou C, Eitel I, Baessler A, Steinhagen-Thiessen E, Koenig W, Schulze PC, Landmesser U, Laufs U, Weingärtner O. High interindividual variability in LDL-cholesterol reductions after inclisiran administration in a real-world multicenter setting in Germany. Clin Res Cardiol 2023;112:1639-1649. doi: 10.1007/s00392-023-02247-8


Ali JH, Walter MCombining old and new concepts in targeting telomerase for cancer therapy: transient, immediate, complete and combinatory attack (TICCA). Cancer Cell Int 2023;7;23:197. doi: 10.1186/s12935-023-03041-2


Revskij D, Runst J, Umstätter C, Ehlers L, Rohde S, Zechner D, Bastian M, Müller-Hilke B, Fuellen G, Henze L, Murua Escobar H, Junghanss C, Kowald A, Walter U, Köhling R, Wolkenhauer O, Jaster R, Uncoupling protein 2 deficiency of non-cancerous tissues inhibits the progression of pancreatic cancer in mice. Hepatobiliary Pancreat Dis Int 2023;22:190-199. DOI: 10.1016/j.hbpd.2022.12.003 

Möller S, Saul N, Projahn E, Barrantes I, Gézsi A, Walter M, Antal P, FuellenG. Gene co-expression analyses of health(span) across multiple speciesNAR GenomBioinform 2022;4:lqac083; DOI:10.1093/nargab/lqac083 


Boecking B, Klasing S, Walter M, Brueggemann P, Nyamaa A, Rose M, Mazurek B. Vascular-metabolic risk factors and psychological stress in patients with chronic tinnitus. Nutrients 2022,14,2256; DOI: 10.3390/nu14112256 


Lin H, Mensch J, Haschke M, Jäger K, Köttgen B, Dernedde J, Orsó E, Walter M. Establishment and characterization of hTERT immortalized Hutchinson–Gilford Progeria fibroblast cell lines.Cells 2022;11;2784; DOI: 10.3390/cells11182784 


Jäger K, Mensch J, GrimmigMA, Neuner B, Gorzelniak K, Türkmen S, Demuth I, Hartmann A, Hartmann C, Wittig F, Sporbert A, Hermann A, Fuellen G, Möller S, Walter M.A conserved long-distance telomeric silencing mechanism suppresses mTOR signaling in aging human fibroblasts.Science Advances 2022;8:eabk2814; DOI: 10.1126/sciadv.abk2814 


Ehlers L, Netz LAW, Reiner J, Berlin P, Bannert K, Bastian M, Zechner D, Lamprecht G, Jaster R. Effects of bile duct ligation and ghrelin treatment on the colonic barrier and microbiome of mice. Pharmacology 2022;107:564-573. DOI: 10.1159/000527142 


Gerstorf D, Ram N, Drewelies J, Duezel S, Eibich P, Steinhagen-Thiessen E, Liebig S, Goebel J, Demuth I, Villringer A, Wagner GG, Lindenberger U, Ghisletta P. Today's older adults are cognitively fitter than older adults were 20 years ago, but when and how they decline is no different than in the past.Psychol Sci 2023;34:22-34; DOI: 10.1177/09567976221118541 


Schwarz A, Demuth I, Landmesser U, Haghikia A, König M, Steinhagen-Thiessen E. Low-density lipoprotein cholesterol goal attainment in patients with clinical evidence of familial hypercholesterolemia and elevated Lp(a)Lipids Health Dis 21:114; DOI: 10.1186/s12944-022-01708-9 

 

Heinisch PP, Mihalj M, Huber M, Schefold JC, HartmannA, Walter M, Steinhagen-Thiessen E, Schmidli J, Stüber F, Räber L, Luedi MM. Impact of lipoprotein(a) levels on perioperative outcomes in cardiac surgery. Cells 2022;11:2784; DOI:10.3390/cells10112829 


Hecker M, Fitzner B, Jäger K, Bühring J, Schwartz M, Hartmann A, WalterM, ZettlUK. Leukocyte telomere length in patients with multiple sclerosis and its association with clinical phenotypes. Mol Neurobiol 2021;58:2886-2896; DOI:10.1007/s12035-021-02315-y 


HartmannA, Hartmann C, Secci R, Hermann A, Fuellen G, Walter M. Ranking biomarkers of aging by citation profiling and effort scoring. Front Genet 2021;21:12:686320; DOI:10.3389/fgene.2021.686320


Walter U, Fuchs M, Grossmann A, Walter M, Thiele T, Storch A, Wittstock M. Adenovirus-vectored COVID-19 vaccine-induced immune thrombosis of carotid artery: a case report. Neurology 2021;97:716-719. DOI: 10.1212/WNL.0000000000012576 


Zimpfer A, Glass Ä, Bastian M, Schuff-Werner P, Hakenberg OW, Maruschke M. Ceruloplasmin expression in renal cell carcinoma correlates with higher-grade and shortened survival. Biomark Med 2021;15:841-850; DOI:10.2217/bmm-2020-0514


Friedrich F, Mueller K, Bruch PG, Hakenberg OW, Bastian M, Almansor S, Willenberg HS, Flow-dependent differentiation of cultured adrenal cells under different stimuli.Cell Tissue Res 2021;384:325–331. DOI:10.1007/s00441-021-03432-9 


Mihalj M, Heinisch PP, Huber M, Schefold JC, Hartmann A, Walter M, Steinhagen-Thiessen E, Schmidli J, Stüber F, Räber L, Luedi MM. Effect of perioperative lipid status on clinical outcomes after cardiac surgeryCells 2021;10:2717. DOI: 10.3390/cells10102717 


Zimmermann M, Yürek S, Konzack R, Walter M, Schober P, Luedi MM, Hönemann C. Delta-Hemoglobin equivalent and granularity Index as cell-derived biomarkers for the detection of bacterial infections. Clin. Lab 2021; 67. DOI: 10.7754/Clin.Lab.2021.210104 

 

Sondermann M, Holecki M, Kirsch AM, Bastian M, Fischer DC, Willenberg HS. Diabetes mellitus and hypertension - A case of sugar and salt?Int J Mol Sci 2020;21:5; DOI: LID - 10.3390/ijms21155200 


Hoeflich A, Fitzner B, Walz C, Hecker M, Tuchscherer A, Bastian M, Brenmoehl J, Schröder I, Willenberg HS, Reincke M, Zettl UK. Systemic effects by intrathecal administration of triamcinolone acetonide in patients with multiple sclerosis. Front Endocrinol 2020;11:574DOI; 10.3389/fendo.2020.00574


Fuellen G, Liesenfeld O, Kowald A, Barrantes I, Bastian M, Simm A, Jansen L, Tietz-Latza A, Quandt D, Franceschi C, Walter M. The preventive strategy for pandemics in the elderly is to collect in advance samples & data to counteract chronic inflammation (inflammaging)Aging Res Rev 2020;62:101091; DOI: 10.1016/j.arr.2020.101091


Reiner J, Berlin P, Wobar J, Schäffler H, Bannert K, BastianM, Vollmar B, Jaster R, Lamprecht G, Witte M. Teduglutide promotes epithelial tight junction pore function in murine short bowel syndrome to alleviate intestinal insufficiency.Dig Dis Sci 2020;65:3521-3523; DOI: 10.1007/s10620-020-06140-6


Dueck A, Reis O, Bastian M, van Treeck L, Weirich S, Haessler F, Fiedler A, Koelch M, Berger C. Feasibility of a complex setting for assessing sleep and circadian rhythmicity in a fragile X cohort. Front Psychiatry 2020;11:36; DOI: 10.3389/fpsyt.2020.00361


Özçürümez MK, Ambrosch A, Frey O, Haselmann V, Holdenrieder S, Kiehntopf M, Neumaier M, WalterM, Wenzel F, Wölfel R, Renz H. SARS-CoV-2 antibody testing - questions to be asked.J Allergy Clin Immunol 2020;146:35-43; DOI:10.1016/j.jaci.2020.05.020


Habib R, Kim R, Neitzel H, Demuth I, Chrzanowska K, Seemanova E, Faber R, Digweed M, Voss R, JägerK, Sperling K, Walter M. Telomere attrition and dysfunction: a potential trigger of the progeroid phenotype in nijmegen breakage syndrome. Aging 2020;12:12342-12375; DOI: 10.18632/aging.103453


Mannuß S, Schuff-Werner P, Dreißiger K, Burstein C.Inhibition of agonist-induced platelet aggregation by magnesium sulfate warrants its use as an alternative in vitro anticoagulant in pseudothrombocytopenia.Platelets 2020;31:680-684; DOI: 10.1080/09537104.2019.1663804

 

Berlin P, Reiner J, Wobar J, Bannert K, Glass Ä, Walter M, Bastian M, Willenberg HS, Vollmar B, Klar E, Seidler U, Lamprecht G, Witte M. Villus growth, increased intestinal epithelial sodium selectivity, and hyperaldostreronism are mechanisms of adaptation in a murine model of short bowel syndrome. Dig Dis Sci 2019;64:1158-1170;DOI: 10.1007/s10620-018-5420-x 


Neßlauer AM, Gläser A, Gräler M, Engelmann R, Müller-Hilke B, Frank M, Burstein C, Rolfs A, Neidhardt J, Wree A, Witt M, Bräuer AU. A therapy with miglustat, 2-hydroxypropyl-ß-cyclodextrin and allopregnanolone restores splenic cholesterol homeostasis in Niemann-pick disease type C1Lipids Health Dis 2019;18:146; DOI: 10.1186/s12944-019-1088-2