Publikationen

Hartmann A, Secci R, Mensch J, Jäger KSteinhagen-Thiessen E, Barrantes I, Palmer D, Kowald A, Schwarz R, Hinz B, Weber D, Grune T, Hübbe P, Rimbach G, Rudolf H, Walter M, Fuellen G. 2023. High-dose polyphenol-rich nutrition improves lipid and inflammation profiles and triggers apoptotic signaling in healthy elderly people (the ErdBEHR Study). medRxiv; doi: https://doi.org/10.1101/2023.04.03.23287994


Witkowski M, Nemet I, Alamri H, Wilcox J, Gupta N, Nimer N, Haghikia A, Li XS, Wu Y, Saha PP, Demuth I, König M, Steinhagen-Thiessen E, Cajka T, Fiehn O, Landmesser U, Wilson Tang WH, Hazen SL. The artificial sweetener erythritol and cardiovascular event risk. Nat Med 2023;29:710-718; DOI: 10.1038/s41591-023-02223 9  https://pubmed.ncbi.nlm.nih.gov/36849732/ 


Hartmann C, Herling L, HartmannA, Köckritz V, Fuellen G, Walter M, Hermann A. Systematic estimation of biological age of in vitro cell culture systems by an age-associated marker panel. Frontiers in Aging 2023;15:4:1129107; DOI: 10.3389/fragi.2023.1129107 https://pubmed.ncbi.nlm.nih.gov/36873743/


Secci R, Hartmann A, Walter M, Grab HJ, van der Auwera-Palitschka S, Kowald A, Palmer D, Rimbach G, Fuellen G, Barrantes I. Biomarkers of geroprotection and cardiovascular health: An overview of omics studies and established clinical biomarkers in the context of diet. Crit Rev Food Sci Nutr 2023;63:2426-2446; DOI: 10.1080/10408398.2021.1975638 Biomarkers of geroprotection and cardiovascular health: An overview of omics studies and established clinical biomarkers in the context of diet - PubMed (nih.gov)


Ali JH, Abdeen Z, Azmi K, Berman T, Jager K, Barnett-Itzhaki Z, Walter M. Influence of exposure to pesticides on telomere length and pregnancy outcome: diethylphosphates but not Dimethylphosphates are associated with accelerated telomere attrition in a Palestinian cohort. Ecotoxicol Environ Saf 2023;256:114801. doi: 10.1016/j.ecoenv.2023.114801. https://pubmed.ncbi.nlm.nih.gov/36989559/


Makhmudova U, Schatz U, Perakakis N, Kassner U, Schumann F, Axthelm C, Stürzebecher P, Sinning DL, Doevelaar A, Rohn B; Westhoff T, Vogt A, Scholl M, Kästner U, Geiling JA, Stach K, Mensch J, Lorenz E, Paitazoglou C, Eitel I, Baessler A, Steinhagen-Thiessen E, Koenig W, Schulze PC, Landmesser U, Laufs U, Weingärtner O. High interindividual variability in LDL-cholesterol reductions after inclisiran administration in a real-world multicenter setting in Germany. Clin Res Cardiol 2023;112:1639-1649. doi: 10.1007/s00392-023-02247-8. https://pubmed.ncbi.nlm.nih.gov/37422840/


Ali JH, Walter M. Combining old and new concepts in targeting telomerase for cancer therapy: transient, immediate, complete and combinatory attack (TICCA). Cancer Cell Int 2023;7;23:197. doi: 10.1186/s12935-023-03041-2. https://pubmed.ncbi.nlm.nih.gov/37679807/ 


Revskij D, Runst J, Umstätter C, Ehlers L, Rohde S, Zechner D, Bastian M, Müller-Hilke B, Fuellen G, Henze L, Murua Escobar H, Junghanss C, Kowald A, Walter U, Köhling R, Wolkenhauer O, Jaster R, Uncoupling protein 2 deficiency of non-cancerous tissues inhibits the progression of pancreatic cancer in mice. Hepatobiliary Pancreat Dis Int 2023;22:190-199. DOI: 10.1016/j.hbpd.2022.12.003 Uncoupling protein 2 deficiency of non-cancerous tissues inhibits the progression of pancreatic cancer in mice - PubMed (nih.gov)

Möller S, Saul N, Projahn E, Barrantes I, Gézsi A, Walter M, Antal P, FuellenG. Gene co-expression analyses of health(span) across multiple speciesNAR GenomBioinform 2022;4:lqac083; DOI:10.1093/nargab/lqac083 Gene co-expression analyses of health(span) across multiple species - PubMed (nih.gov)


Boecking B, Klasing S, Walter M, Brueggemann P, Nyamaa A, Rose M, Mazurek B. Vascular-metabolic risk factors and psychological stress in patients with chronic tinnitus. Nutrients 2022,14,2256; DOI: 10.3390/nu14112256 Vascular-Metabolic Risk Factors and Psychological Stress in Patients with Chronic Tinnitus - PubMed (nih.gov)


Lin H, Mensch J, Haschke M, Jäger K, Köttgen B, Dernedde J, Orsó E, Walter M. Establishment and characterization of hTERT immortalized Hutchinson–Gilford Progeria fibroblast cell lines. Cells 2022;11;2784; DOI: 10.3390/cells11182784 Establishment and Characterization of hTERT Immortalized Hutchinson-Gilford Progeria Fibroblast Cell Lines - PubMed (nih.gov)


Jäger K, Mensch J, GrimmigMA, Neuner B, Gorzelniak K, Türkmen S, Demuth I, Hartmann A, Hartmann C, Wittig F, Sporbert A, Hermann A, Fuellen G, Möller S, Walter M.A conserved long-distance telomeric silencing mechanism suppresses mTOR signaling in aging human fibroblasts. Science Advances 2022;8:eabk2814; DOI: 10.1126/sciadv.abk2814 A conserved long-distance telomeric silencing mechanism suppresses mTOR signaling in aging human fibroblasts - PubMed (nih.gov)


Ehlers L, Netz LAW, Reiner J, Berlin P, Bannert K, Bastian M, Zechner D, Lamprecht G, Jaster R. Effects of bile duct ligation and ghrelin treatment on the colonic barrier and microbiome of mice. Pharmacology 2022;107:564-573. DOI: 10.1159/000527142 Effects of Bile Duct Ligation and Ghrelin Treatment on the Colonic Barrier and Microbiome of Mice - PubMed (nih.gov)


Gerstorf D, Ram N, Drewelies J, Duezel S, Eibich P, Steinhagen-Thiessen E, Liebig S, Goebel J, Demuth I, Villringer A, Wagner GG, Lindenberger U, Ghisletta P. Today's older adults are cognitively fitter than older adults were 20 years ago, but when and how they decline is no different than in the past.Psychol Sci 2023;34:22-34; DOI: 10.1177/09567976221118541 Today's Older Adults Are Cognitively Fitter Than Older Adults Were 20 Years Ago, but When and How They Decline Is No Different Than in the Past - PubMed (nih.gov)


Schwarz A, Demuth I, Landmesser U, Haghikia A, König M, Steinhagen-Thiessen E. Low-density lipoprotein cholesterol goal attainment in patients with clinical evidence of familial hypercholesterolemia and elevated Lp(a). Lipids Health Dis 21:114; DOI: 10.1186/s12944-022-01708-9 Low-density lipoprotein cholesterol goal attainment in patients with clinical evidence of familial hypercholesterolemia and elevated Lp(a) - PubMed (nih.gov)

 

Heinisch PP, Mihalj M, Huber M, Schefold JC, HartmannA, Walter M, Steinhagen-Thiessen E, Schmidli J, Stüber F, Räber L, Luedi MM. Impact of lipoprotein(a) levels on perioperative outcomes in cardiac surgery. Cells 2022;11:2784; DOI:10.3390/cells10112829 Impact of Lipoprotein(a) Levels on Perioperative Outcomes in Cardiac Surgery - PubMed (nih.gov)


Hecker M, Fitzner B, Jäger K, Bühring J, Schwartz M, Hartmann A, WalterM, ZettlUK. Leukocyte telomere length in patients with multiple sclerosis and its association with clinical phenotypes. Mol Neurobiol 2021;58:2886-2896; DOI:10.1007/s12035-021-02315-y Leukocyte Telomere Length in Patients with Multiple Sclerosis and Its Association with Clinical Phenotypes - PubMed (nih.gov)


HartmannA, Hartmann C, Secci R, Hermann A, Fuellen G, Walter M. Ranking biomarkers of aging by citation profiling and effort scoring. Front Genet 2021;21:12:686320; DOI:10.3389/fgene.2021.686320. Ranking Biomarkers of Aging by Citation Profiling and Effort Scoring - PubMed (nih.gov)


Walter U, Fuchs M, Grossmann A, Walter M, Thiele T, Storch A, Wittstock M. Adenovirus-vectored COVID-19 vaccine-induced immune thrombosis of carotid artery: a case report. Neurology 2021;97:716-719. DOI: 10.1212/WNL.0000000000012576 Adenovirus-Vectored COVID-19 Vaccine-Induced Immune Thrombosis of Carotid Artery: A Case Report - PubMed (nih.gov)


Zimpfer A, Glass Ä, Bastian M, Schuff-Werner P, Hakenberg OW, Maruschke M. Ceruloplasmin expression in renal cell carcinoma correlates with higher-grade and shortened survivalBiomark Med 2021;15:841-850; DOI:10.2217/bmm-2020-0514. Ceruloplasmin expression in renal cell carcinoma correlates with higher-grade and shortened survival - PubMed (nih.gov)


Friedrich F, Mueller K, Bruch PG, Hakenberg OW, Bastian M, Almansor S, Willenberg HS, Flow-dependent differentiation of cultured adrenal cells under different stimuli. Cell Tissue Res 2021;384:325–331. DOI:10.1007/s00441-021-03432-9 Flow-dependent differentiation of cultured adrenal cells under different stimuli - PubMed (nih.gov)


Mihalj M, Heinisch PP, Huber M, Schefold JC, Hartmann A, Walter M, Steinhagen-Thiessen E, Schmidli J, Stüber F, Räber L, Luedi MM. Effect of perioperative lipid status on clinical outcomes after cardiac surgery. Cells 2021;10:2717. DOI: 10.3390/cells10102717  Effect of Perioperative Lipid Status on Clinical Outcomes after Cardiac Surgery - PubMed (nih.gov)


Zimmermann M, Yürek S, Konzack R, Walter M, Schober P, Luedi MM, Hönemann C. Delta-Hemoglobin equivalent and granularity Index as cell-derived biomarkers for the detection of bacterial infections. Clin. Lab 2021; 67. DOI: 10.7754/Clin.Lab.2021.210104 Delta-Hemoglobin Equivalent and Granularity Index as Cell-Derived Biomarkers for the Detection of Bacterial Infections - PubMed (nih.gov)

 

Sondermann M, Holecki M, Kirsch AM, Bastian M, Fischer DC, Willenberg HS. Diabetes mellitus and hypertension - A case of sugar and salt? Int J Mol Sci 2020;21:5; DOI: LID - 10.3390/ijms21155200 https://pubmed.ncbi.nlm.nih.gov/32708014/


Hoeflich A, Fitzner B, Walz C, Hecker M, Tuchscherer A, Bastian M, Brenmoehl J, Schröder I, Willenberg HS, Reincke M, Zettl UK. Systemic effects by intrathecal administration of triamcinolone acetonide in patients with multiple sclerosis. Front Endocrinol 2020;11:574DOI; 10.3389/fendo.2020.00574.Systemic Effects by Intrathecal Administration of Triamcinolone Acetonide in Patients With Multiple Sclerosis - PubMed (nih.gov)


Fuellen G, Liesenfeld O, Kowald A, Barrantes I, Bastian M, Simm A, Jansen L, Tietz-Latza A, Quandt D, Franceschi C, Walter M. The preventive strategy for pandemics in the elderly is to collect in advance samples & data to counteract chronic inflammation (inflammaging)Aging Res Rev 2020;62:101091; DOI: 10.1016/j.arr.2020.101091;The preventive strategy for pandemics in the elderly is to collect in advance samples & data to counteract chronic inflammation (inflammaging) - PubMed (nih.gov)


Reiner J, Berlin P, Wobar J, Schäffler H, Bannert K, BastianM, Vollmar B, Jaster R, Lamprecht G, Witte M. Teduglutide promotes epithelial tight junction pore function in murine short bowel syndrome to alleviate intestinal insufficiency.Dig Dis Sci 2020;65:3521-3523; DOI: 10.1007/s10620-020-06140-6 Teduglutide Promotes Epithelial Tight Junction Pore Function in Murine Short Bowel Syndrome to Alleviate Intestinal Insufficiency - PubMed (nih.gov)


Dueck A, Reis O, Bastian M, van Treeck L, Weirich S, Haessler F, Fiedler A, Koelch M, Berger C. Feasibility of a complex setting for assessing sleep and circadian rhythmicity in a fragile X cohort. Front Psychiatry 2020;11:36; DOI: 10.3389/fpsyt.2020.00361. Feasibility of a Complex Setting for Assessing Sleep and Circadian Rhythmicity in a Fragile X Cohort - PubMed (nih.gov)


Özçürümez MK, Ambrosch A, Frey O, Haselmann V, Holdenrieder S, Kiehntopf M, Neumaier M, WalterM, Wenzel F, Wölfel R, Renz H. SARS-CoV-2 antibody testing - questions to be asked.J Allergy Clin Immunol 2020;146:35-43; DOI:10.1016/j.jaci.2020.05.020. SARS-CoV-2 antibody testing-questions to be asked - PubMed (nih.gov)


Habib R, Kim R, Neitzel H, Demuth I, Chrzanowska K, Seemanova E, Faber R, Digweed M, Voss R, JägerK, Sperling K, Walter M. Telomere attrition and dysfunction: a potential trigger of the progeroid phenotype in nijmegen breakage syndrome. Aging 2020;12:12342-12375; DOI: 10.18632/aging.103453. Telomere attrition and dysfunction: a potential trigger of the progeroid phenotype in nijmegen breakage syndrome - PubMed (nih.gov)


Mannuß S, Schuff-Werner P, Dreißiger K, Burstein C.Inhibition of agonist-induced platelet aggregation by magnesium sulfate warrants its use as an alternative in vitro anticoagulant
in pseudothrombocytopenia.Platelets 2020;31:680-684; DOI: 10.1080/09537104.2019.1663804. Inhibition of agonist-induced platelet aggregation by magnesium sulfate warrants its use as an alternative in vitro anticoagulant in pseudothrombocytopenia - PubMed (nih.gov)

 

Berlin P, Reiner J, Wobar J, Bannert K, Glass Ä, Walter M, Bastian M, Willenberg HS, Vollmar B, Klar E, Seidler U, Lamprecht G, Witte M. Villus growth, increased intestinal epithelial sodium selectivity, and hyperaldostreronism are mechanisms of adaptation in a murine model of short bowel syndrome. Dig Dis Sci 2019;64:1158-1170;DOI: 10.1007/s10620-018-5420-xhttps://pubmed.ncbi.nlm.nih.gov/30569336/


Neßlauer AM, Gläser A, Gräler M, Engelmann R, Müller-Hilke B, Frank M, Burstein C, Rolfs A, Neidhardt J, Wree A, Witt M, Bräuer AU. A therapy with miglustat, 2-hydroxypropyl-ß-cyclodextrin and allopregnanolone restores splenic cholesterol homeostasis in Niemann-pick disease type C1. Lipids Health Dis 2019;18:146; DOI: 10.1186/s12944-019-1088-2 https://pubmed.ncbi.nlm.nih.gov/31248418/